Q&A on the investigational vaccine candidate M72/AS01E

1. What is the M72/AS01E vaccine candidate? M72/AS01E is a subunit vaccine comprised of an immunogenic fusion protein (M72) derived from two Mycobacterium tuberculosis (M.tb) antigens (MTB32A and MTB39A), and the GlaxoSmithKline (GSK) proprietary adjuvant AS01E. AS01E is the same adjuvant used in Shingrix GSK vaccine, as well as in the new malaria vaccine RTS,S/AS01E.
2. Who developed and who manufactured the vaccine? The M72/AS01E vaccine candidate is being developed by the pharmaceutical company GlaxoSmithKline, in partnership with AERAS. AERAS is a not for profit organization based in the US, aimed at supporting tuberculosis vaccine research, funded by the Bill and Melinda Gates foundation, the UK Department for International Development (DFID), and other organizations.
3. What is…

Q&A with Dr Ann Moen: How influenza preparedness helps fight other infectious diseases

Dr Moen is Chief of the WHO’s Influenza Preparedness & Response Unit (IPR) What lessons does influenza preparedness offer for tackling respiratory pathogens and other diseases? Capacity building for influenza is critical because if you can prepare for and respond to flu outbreaks or respiratory events, you learn and practice for responses to other emerging diseases. Flu is not a sporadic outbreak like Ebola or Zika. It is always there, so there is always something to practice with and keep skills sharp. Because flu is a continual threat there is a lot of learning that goes on which also supports work on other emerging diseases. It’s like the basic architecture for capacity building in all areas. For…

Committing to End TB in Children, Adolescents and Families

Henriette Fore, Executive Director, UNICEF, and Tedros Adhanom Ghebreyesus, Director-General, WHO, holding the Roadmap poster
On the eve of the 73rd UN General Assembly, UNICEF, WHO and the Stop TB Partnership hosted a side-event to show commitment and accelerate action towards ending TB in children, adolescents and families. Co-sponsored by the Permanent Mission of Japan to the United Nations, the Danish Ministry of Health, the Permanent Mission of Nigeria to the United Nations, TB Alliance, Louder Than TB, Treatment Action Group, Unitaid, the Global Fund, USAID, Elizabeth Glaser Pediatric AIDS Foundation, JHPIEGO, The Union, KNCV Tuberculosis Foundation and Every Woman Every Child, the event aimed to show commitment and accelerate action towards ending TB in…

Viet Nam on track to End TB

Viet Nam Health Minister Nguyễn Thị Kim Tiến addresses the UN High Level Meeting on TB in New York
Viet Nam Health Minister Nguyễn Thị Kim Tiến joined Head of States, Ministers and other leaders at the first-ever United Nations High-Level Meeting on TB on 26th September at the 2018 General Assembly in New York. She delivered a powerful statement of commitment to action during the plenary, and at a media briefing on the High Level Meeting.

“Viet Nam will do its best to achieve reductions in mortality and morbidity, by introducing new tools, new drugs, new approaches with high political commitment and by strengthening the health system, especially at the grassroots level, through…